Numbuzin No.3 and No.5 skincare is up to 28% off at the brand's store. Prices checked October 6, 2026.

    Brand

    SkinMedica

    Known for growth-factor skincare, especially the TNS serums (TNS Recovery Complex, TNS Advanced+).
    SkinMedica logo

    SkinMedica was founded in 1999 and became known for growth-factor skincare built on its proprietary TNS (tissue nutrient solution) technology. Allergan acquired it in 2012, and it is now part of Allergan Aesthetics, an AbbVie company.

    Founded

    1999

    Founder

    Founded in Carlsbad, California (dermatology-led)

    Headquarters

    Founded in Carlsbad, California; now under Allergan Aesthetics (Irvine, CA)

    Ownership

    Owned by Allergan Aesthetics, an AbbVie company

    Ownership and scale

    Allergan acquired SkinMedica in November 2012 for $350 million plus up to $25 million in contingent payments. It joined AbbVie when AbbVie acquired Allergan in 2020. Current standalone valuation is not publicly disclosed.

    Brand timeline

    1. 1999

      Founded in Carlsbad, California

    2. 2001

      Launches TNS Recovery Complex, an early growth-factor serum

    3. 2012

      Allergan acquires SkinMedica for $350M (plus up to $25M contingent)

    4. 2020

      Becomes part of AbbVie after AbbVie acquires Allergan

    Where to buy

    Brand siteDermstoreAuthorized dermatology and medspa officesSkinStore

    Where to get the best offers

    A professional-channel brand: look for authorized-retailer promotions at Dermstore and SkinStore, brand-site value sets and auto-ship, and Alle loyalty rewards. Buy only from authorized sellers to avoid counterfeit or expired product.

    SkinMedica products we have reviewed

    SkinMedica HA5 Hydra Collagen Hydrator with Vegan Collagen
    professional

    HA5 Hydra Collagen Hydrator with Vegan Collagen

    SkinMedica

    Key Ingredient

    Proprietary HA5 Hydra Collagen Complex

    Key ingredients named by the brand: Proprietary HA5 Hydra Collagen Complex, Advanced VITISENSCE Technology and Avocado Oil EstersNo fragrance listed in the ingredient listHydrator in pump bottle, applied after treatment products and before moisturizer, 1.7 fl oz (50ml)
    $192.00/ 1.7 fl oz (50ml)($3.84/ml)
    SkinMedica Retinol Complex 0.5
    professional

    Retinol Complex 0.5

    SkinMedica

    Key Ingredient

    Retinol

    Key ingredients named by the brand: Retinol and PhytoShield ComplexNo fragrance listed in the ingredient listEvening retinol treatment in pump bottle, applied before moisturizer, 1 fl oz (30ml)
    $80.00/ 1 fl oz (30ml)($2.67/ml)
    SkinMedica Neck Correct Neck and Décolleté Cream
    professional

    Neck Correct Neck and Décolleté Cream

    SkinMedica

    Key Ingredient

    Green Microalgae Extract

    Key ingredients named by the brand: Green Microalgae Extract, Shiitake Mushroom Extract and Rice ProteinNo fragrance listed in the ingredient listNeck and décolleté cream in pump bottle, 1.7 fl oz (50ml)
    $135.00/ 1.7 fl oz (50ml)($2.70/ml)
    SkinMedica TNS Advanced+ Serum
    luxury

    TNS Advanced+ Serum

    SkinMedica

    Key Ingredient

    Next-generation TNS growth factor blend

    Patients felt 6 years younger (psychometric, 12 weeks)Addresses sagging skin at 8 weeksProgressive results through 24 weeks
    $295.00/ 1 fl oz (30ml)($9.83/ml)

    Brand background is compiled from public sources. Ownership and valuation figures are reported acquisitions or valuations where disclosed; private brands are marked as not publicly disclosed. Prices and retailers change, so confirm on the brand's official page.