BLC

    Ingredient deep dive

    NAD+

    Also seen as: Nicotinamide Adenine Dinucleotide
    All ingredients

    What it does

    A coenzyme found in every living cell that supports energy production (ATP) and DNA repair. Levels decline with age, which is why it has become a popular longevity ingredient.

    Best for

    Mature skin and routine-builders looking for emerging longevity-science ingredients. Used in numbuzin's No.9 line and in Medik8's Pro-Collagen+ Peptide Cream as 'NAD+ Longevity Booster'.

    The full picture

    NAD+ levels decline as we age, and that decline has been linked to the visible and cellular signs of aging. Oral NAD+ precursors (nicotinamide riboside, nicotinamide mononucleotide) have a decade of supplementation research behind them. Topical NAD+ is much newer and the open question is whether the molecule can meaningfully cross the stratum corneum to affect cellular processes in living skin. The brands using it position it as a longevity ingredient rather than a wrinkle-reduction active. Treat current marketing claims as emerging science rather than established proof.

    Evidence

    NAD+ supplementation has been linked to cellular repair and energy metabolism. Topical efficacy on human skin is still emerging research.

    Read the source: PubMed: NAD+ in aging biology ->

    Lifting creams featuring NAD+

    Medik8 Advanced Pro-Collagen+ Peptide Cream
    professional
    Vegan
    CF

    Advanced Pro-Collagen+ Peptide Cream

    Medik8

    Key Ingredient

    GF MiniProtein

    Visibly improves firmness in 7 daysPregnancy and nursing safe (non-retinoid alternative)Vegan Society certified
    $98.00/ 1.6 oz (48g)($2.04/ml)
    numbuzin No.9 NAD+ BIO Lifting-sil Essence
    k-beauty
    Vegan
    CF

    No.9 NAD+ BIO Lifting-sil Essence

    numbuzin

    Key Ingredient

    NAD+

    Reduces 11 types of wrinkles (brand-cited 4-wk study)Buy 2 for extra 25% off, Buy 3 for 30% offNo animal-derived ingredients, no gluten
    $33.00/ 1.69 fl oz (50ml)($0.66/ml)