ZO Skin Health Daily Power Defense Review
BLC Research Score
A research-based assessment from ingredient and formula analysis plus reputation, not a hands-on lab test. See our scoring approach.
- Best for
- dry, oily, combination, sensitive
- Price
- $190.00 / 1.7 fl oz (50ml)
- Main claim
- Anti-aging firming
- Texture
- Described as a multi-action antioxidant serum; 1-2 pumps AM and PM.
Editorial pick only.
Quick verdict
ZO Skin Health Daily Power Defense sits in the professional tier at $190.00 for 1.7 fl oz (50ml). Best for dry, oily, combination, sensitive skin.
Key ingredients
What the hero actives in Daily Power Defense are supposed to do.
Primary
Vitamins A + E
Supporting
ZO-RRS2, ZPOLY, Micrococcus lysate, arabidopsis thaliana extract
Learn more about these actives
Vitamin C
An antioxidant that neutralizes free radicals from UV and pollution, while also brightening dark spots and supporting collagen synthesis.
Read the full Vitamin C guide ->Vitamin E
A fat-soluble antioxidant that neutralizes free radicals from UV and pollution, supports skin barrier function, and keeps the oils in a formula from going rancid.
Read the full Vitamin E guide ->Alternatives to ZO Skin Health Daily Power Defense
Other face serums we have reviewed.
ALASTIN
C-RADICAL Defense Antioxidant Serum
$218.00 / Full size
Read review ->ALASTIN
A-LUMINATE Brightening Serum
$198.00 / Full size
Read review ->Biodance
Pore Perfecting Collagen Peptide Serum
$21.90 / 1.01 fl oz (30ml)
Read review ->CeraVe
Resurfacing Retinol Serum
$21.99 / 1 fl oz (30ml)
Read review ->See category roundups:
Final verdict
ZO Skin Health Daily Power Defense is a professional face serum for dry, oily, combination, sensitive skin.
Check price at ZOIndependent. No sponsored placement.
Comparing options? See all our tested picks on the BestLiftingCream.com homepage.
Editor's note
Reviewed by the BLC Editorial Team using our standardized 7-criteria scoring methodology. Independent and not sponsored.
Last updated: Sep 17, 2026. Read how we evaluate.